During cancer treatment, many patients experience weight loss, muscle wasting, and decreased physical strength—a condition known as “sarcopenia.” This not only affects quality of life but may also reduce treatment tolerance and prognosis. Recent research shows that sarcopenia is quite common among cancer patients, particularly pronounced in those undergoing chemotherapy or long-term treatment. Causes of sarcopenia include decreased appetite, increased inflammatory responses, and reduced physical activity, among other multiple factors. Therefore, early prevention and intervention is not just about improving physical strength—it is an important component of overall treatment success [1].
The latest medical research indicates that nutrition and exercise are the two core strategies for preventing sarcopenia. A study published in the Journal of Cachexia, Sarcopenia and Muscle showed that adequate protein intake (especially containing essential amino acids) helps maintain muscle mass and may reduce muscle loss during treatment [2]. Another 2022 review study published in IJERPH indicated that combining resistance training (such as simple weight training) with nutritional supplementation can significantly improve cancer-related sarcopenia and fatigue [3]. These findings emphasize that diet or exercise alone has limited effect—combining both achieves the best results.
Therefore, during cancer treatment, patients are advised to maintain regular and moderate activity, such as performing 2–3 sessions of light resistance training per week (such as resistance bands or bodyweight exercises), combined with daily walking, to promote muscle maintenance. At the same time, diet should pay special attention to protein intake, such as fish, eggs, legumes, or dairy products; if necessary, medical nutritional supplements can be added under the guidance of a dietitian. If loss of appetite or continuous weight loss occurs, discuss this with the medical team early to avoid delaying intervention. Additionally, avoid prolonged bed rest or complete cessation of activity, as even short periods of inactivity can accelerate muscle loss. Overall, through the strategy of “appropriate exercise + adequate nutrition,” the risk of sarcopenia can be effectively reduced, helping patients complete their treatment more smoothly.
References
Liu R., et al. (2025). Global trends in sarcopenia and cancer over the past 10 years: a bibliometric analysis. Discover Oncology.
van de Worp WR, et al. (2020). Nutritional and Exercise Interventions in Cancer-Related Cachexia: An Extensive Narrative Review. Frontiers in Nutrition.
Clemente-Suárez VJ, et al. (2022). Nutritional and Exercise Interventions in Cancer-Related Cachexia: An Extensive Narrative Review. Int J Environ Res Public Health.